Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CCKAR | P32238 | 1/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4321530 | 1.00 | PPARG (0.48) | PPARGPPARAHTR1AADORA3CCKAR | |
| SCHEMBL4323726 | 0.76 | HTR1A (0.74) | PPARGPPARAHTR1AADORA3CCKAR | |
| SCHEMBL13626294 | 0.76 | HTR1A (0.74) | PPARGPPARAHTR1AADORA3CCKAR | |
| SCHEMBL5037131 | 0.73 | PPARG (0.64) | PPARGPPARAKMOLMNA | |
| SCHEMBL13627044 | 0.73 | POLB (0.52) | PPARGPPARAHTR1AADORA3CCKAR | |
| SCHEMBL4313684 | 0.73 | POLB (0.52) | PPARGPPARAHTR1AADORA3CCKAR | |
| SCHEMBL4318071 | 0.73 | SMN1; SMN2 (0.54) | MAPTTDP1SMN1; SMN2 | |
| SCHEMBL13626448 | 0.73 | SMN1; SMN2 (0.54) | MAPTTDP1SMN1; SMN2 | |
| SCHEMBL17428488 | 0.71 | PPARG (0.49) | PPARGPPARAHTR1AADORA3CCKAR | |
| SCHEMBL22738916 | 0.71 | MRGPRX4 (0.39) | TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138416-A1 | OXIME CARBAMOYL DERIVATIVES AS MODULATORS OF FATTY ACID AMIDES HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-11-19 | — | — | WO | disclosed |