Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | CCKAR | P32238 | 1/20 | 0.55 |
| ▸ | HTR5A | P47898 | 1/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | GRK5 | P34947 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316717 | 0.85 | LTA4H (0.46) | HTR1AADORA3CCKARHTR5AKCNH2 | |
| SCHEMBL4052204 | 0.80 | FYN (0.57) | HTR1AADORA3CCKARHTR5APRMT6 | |
| SCHEMBL8578010 | 0.80 | HTR1A (0.48) | HTR1AADORA3CCKARHTR5APRMT6 | |
| SCHEMBL27623947 | 0.76 | KAT6A (0.55) | HTR1AADORA3CCKARHTR5APRMT6 | |
| SCHEMBL4327798 | 0.75 | KMO (0.52) | CYP2D6CYP2C19 | |
| SCHEMBL8310029 | 0.75 | KMO (0.52) | CYP2D6CYP2C19 | |
| SCHEMBL940399 | 0.75 | KAT6A (0.57) | HTR1AADORA3CCKARHTR5AKAT6A | |
| SCHEMBL31222146 | 0.75 | KAT6A (0.57) | HTR1AADORA3CCKARHTR5AKAT6A | |
| SCHEMBL1334921 | 0.74 | KCNH2 (0.59) | PRMT6KAT6AKCNH2CYP3A4CYP2C9 | |
| SCHEMBL4559856 | 0.73 | AR (0.52) | HTR1AADORA3CCKARHTR5AKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138416-A1 | OXIME CARBAMOYL DERIVATIVES AS MODULATORS OF FATTY ACID AMIDES HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-11-19 | — | — | WO | disclosed |