Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29642739 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1NAMPTHPGD | |
| SCHEMBL30876286 | 0.82 | KEAP1 (0.56) | ALDH1A1KMT2AMEN1NAMPTCYP11B1 | |
| SCHEMBL13637271 | 0.76 | CA12 (0.51) | PTGER2 | |
| SCHEMBL13398723 | 0.76 | PTGER2 (0.54) | PTGER2 | |
| SCHEMBL13420292 | 0.76 | PTGER2 (0.52) | PTGER2 | |
| SCHEMBL5049401 | 0.76 | PTGER2 (0.51) | PTGER2 | |
| SCHEMBL13398734 | 0.75 | PTGER2 (0.54) | PTGER2 | |
| SCHEMBL5043275 | 0.75 | PTGER2 (0.46) | PTGER2 | |
| SCHEMBL4945973 | 0.75 | CA12 (0.58) | PTGER2 | |
| SCHEMBL12077955 | 0.74 | NAPRT (0.50) | ALDH1A1MAPK1HPGDHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622475-B2 | EP2 agonists | PFIZER INC (US) | 2009-11-24 | — | — | US | disclosed |
| US-7622475-B2 | EP2 agonists | PFIZER INC (US) | 2009-11-24 | — | — | US | disclosed |