Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28773435 | 0.89 | TAS2R14 (0.61) | KEAP1NFE2L2ALDH1A1MAPTTAS2R14 | |
| SCHEMBL29910182 | 0.89 | TAS2R14 (0.61) | KEAP1NFE2L2ALDH1A1MAPTTAS2R14 | |
| SCHEMBL29642739 | 0.86 | ALDH1A1 (0.62) | ALDH1A1KMT2AMAPTCYP11B1MEN1 | |
| SCHEMBL30014545 | 0.83 | APLNR (0.51) | KMT2ATAS2R14MEN1CXCR3NAMPT | |
| SCHEMBL14285692 | 0.83 | TAS2R14 (0.64) | ALDH1A1TAS2R14CXCR3APLNR | |
| SCHEMBL13626593 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KMT2AMAPTCYP11B1MEN1 | |
| SCHEMBL30655988 | 0.79 | APLNR (0.48) | KMT2ATAS2R14MEN1CXCR3APLNR | |
| SCHEMBL22265923 | 0.77 | ALDH1A1 (0.66) | ALDH1A1KMT2AMAPTTAS2R14MEN1 | |
| SCHEMBL28413113 | 0.77 | NAMPT (0.64) | KEAP1NFE2L2ALDH1A1NAMPT | |
| SCHEMBL12077955 | 0.76 | NAPRT (0.50) | KEAP1NFE2L2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024099435-A1 | TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2024-05-16 | — | — | WO | disclosed |
| CN-118005606-A | TEAD inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-05-10 | — | — | CN | disclosed |