Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807690 | 0.80 | HPGD (0.44) | HPGDHSD17B10KDM4EALDH1A1GAA | |
| SCHEMBL893113 | 0.80 | HPGD (0.44) | HPGDHSD17B10KDM4EALDH1A1GAA | |
| SCHEMBL14008505 | 0.78 | HPGD (0.47) | HPGDHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL23638591 | 0.76 | HPGD (0.42) | HPGDHSD17B10KDM4EALDH1A1GAA | |
| SCHEMBL11930746 | 0.76 | HPGD (0.42) | HPGDHSD17B10KDM4EALDH1A1GAA | |
| SCHEMBL15216746 | 0.76 | ALDH1A1 (0.46) | HPGDHSD17B10ALDH1A1 | |
| SCHEMBL12895706 | 0.74 | HPGD (0.41) | HPGDHSD17B10KDM4E | |
| SCHEMBL12013420 | 0.73 | ADRA2A (0.41) | HPGDHSD17B10 | |
| SCHEMBL11315118 | 0.70 | HPGD (0.48) | HPGDHSD17B10KDM4EALDH1A1GAA | |
| SCHEMBL8750400 | 0.70 | CYP1A2 (0.39) | HPGDHSD17B10ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009142967-A1 | THERAPEUTIC PROSTAGLANDIN COMPOUNDS USED AS OCULAR HYPOTENSIVE AGENTS | ALLERGAN, INC. (US) | 2009-11-26 | — | — | WO | disclosed |