Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18915652 | 0.95 | ALDH1A1 (0.44) | DGKAMAPK1MAPTRECQLALDH1A1 | |
| SCHEMBL9978168 | 0.92 | MAPK1 (0.44) | DGKAMAPK1MAPTRECQLALDH1A1 | |
| SCHEMBL18224033 | 0.91 | HTR2C (0.49) | DGKAMAPK1MAPTRECQLALDH1A1 | |
| SCHEMBL14286265 | 0.90 | HTR2C (0.51) | DGKAMAPTRECQLALDH1A1KMT2A | |
| SCHEMBL7954092 | 0.89 | DGKA (0.40) | DGKAMAPK1MAPTRECQLALDH1A1 | |
| SCHEMBL2574904 | 0.87 | KMT2A (0.46) | DGKAKMT2ASMN1; SMN2PRKCAGAA | |
| SCHEMBL15760609 | 0.86 | PRKCA (0.33) | DGKAMAPK1MAPTRECQLALDH1A1 | |
| SCHEMBL6358200 | 0.86 | CYP1A2 (0.46) | ALDH1A1KMT2ASMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL12060996 | 0.86 | ALDH1A1 (0.41) | DGKAMAPK1MAPTALDH1A1KMT2A | |
| SCHEMBL914307 | 0.85 | KMT2A (0.51) | DGKAKMT2ASMN1; SMN2PRKCANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615593-B2 | Comprises interpenetrating polymer network/matrix (of collagen and/or gelatin) modified with endcapped polyalkylene glycol; drug delivery; for incorporation into bandages, surgical and dental wound packing material, diapers and catamenial devices | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-11-10 | — | — | US | disclosed |