Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627386 | 0.95 | DGKA (0.46) | ALDH1A1MAPK1DGKAMAPTRECQL | |
| SCHEMBL18224033 | 0.95 | HTR2C (0.49) | ALDH1A1MAPK1DGKAMAPTRECQL | |
| SCHEMBL14286265 | 0.94 | HTR2C (0.51) | ALDH1A1DGKAMAPTRECQLHTR2C | |
| SCHEMBL12060996 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MAPK1DGKAMAPTHTR2C | |
| SCHEMBL9978168 | 0.88 | MAPK1 (0.44) | ALDH1A1MAPK1DGKAMAPTRECQL | |
| SCHEMBL141048 | 0.87 | ADRA2A (0.36) | ALDH1A1DGKAMAPTSMN1; SMN2 | |
| SCHEMBL15760611 | 0.86 | PRKCA (0.33) | ALDH1A1MAPK1DGKAMAPTRECQL | |
| SCHEMBL9329901 | 0.86 | DGKA (0.37) | ALDH1A1DGKAMAPTHTR2CPRKCA | |
| SCHEMBL2574904 | 0.85 | KMT2A (0.46) | DGKAKMT2ASMN1; SMN2PRKCAGAA | |
| SCHEMBL18915762 | 0.85 | ALDH1A1 (0.38) | ALDH1A1MAPK1DGKAMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4252787-A1 | MEDICAL HYDROGEL AND PREPARATION METHOD THEREFOR AND USE THEREOF | Beijing Biosis Healing Biological Technology Co., Ltd. (CN) | 2023-10-04 | — | — | EP | disclosed |
| US-11020386-B2 | Methods and compositions for preventing opioid abuse | ALBANY MOLECULAR RESEARCH, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| US-10695342-B2 | Methods and compositions for preventing opioid abuse | ALBANY MOLECULAR RESEARCH, INC. (US) | 2020-06-30 | — | — | US | disclosed |
| US-10226456-B2 | Methods and compositions for preventing opioid abuse | 3ST RESEARCH LLC (US) | 2019-03-12 | — | — | US | disclosed |
| US-20170157116-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE | CURIA BUFFALO R&D, LLC | 2017-06-08 | — | — | US | disclosed |
| US-20170151232-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE | CURIA BUFFALO R&D, LLC | 2017-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10226456-B2 | Methods and compositions for preventing opioid abuse | OPRM1, OPRK1, OPRD1 | ALDH1A1 66/4885MAPK1 4617/4885DGKA 2818/4885 |
| US-10695342-B2 | Methods and compositions for preventing opioid abuse | OPRM1, OPRK1, OPRD1 | ALDH1A1 66/4885MAPK1 4617/4885DGKA 2818/4885 |
| US-11020386-B2 | Methods and compositions for preventing opioid abuse | OPRM1, OPRK1, OPRD1 | ALDH1A1 66/4885MAPK1 4617/4885DGKA 2818/4885 |
| US-20170157116-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE | OPRM1, OPRK1, OPRD1 | ALDH1A1 66/4885MAPK1 4617/4885DGKA 2818/4885 |
| US-20170151232-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE | OPRM1, OPRK1, OPRD1 | ALDH1A1 66/4885MAPK1 4617/4885DGKA 2818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.