Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627814 | 0.84 | PPARG (0.41) | KCNH2HRH3KMT2AMEN1NAMPT | |
| SCHEMBL13627677 | 0.79 | TRPV1 (0.37) | NAMPT | |
| SCHEMBL13628370 | 0.78 | NPC1 (0.44) | KCNH2HRH3KMT2AMEN1NAMPT | |
| SCHEMBL2549704 | 0.77 | KCNH2 (0.52) | KCNH2HRH3KMT2AMEN1NAMPT | |
| SCHEMBL2246819 | 0.77 | KCNH2 (0.52) | KCNH2HRH3KMT2AMEN1NAMPT | |
| SCHEMBL13627657 | 0.77 | TRPV1 (0.38) | NAMPT | |
| SCHEMBL13628365 | 0.74 | CCR1 (0.47) | KMT2AMEN1CCR1 | |
| SCHEMBL2249633 | 0.73 | MMP2 (0.55) | KCNH2HRH3KMT2AMEN1NAMPT | |
| SCHEMBL2545082 | 0.73 | MMP2 (0.55) | KCNH2HRH3KMT2AMEN1NAMPT | |
| SCHEMBL13627581 | 0.73 | NAMPT (0.39) | KCNH2HRH3KMT2AMEN1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618970-B2 | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2009-11-17 | — | — | US | disclosed |