Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.37 |
| ▸ | NAMPT | P43490 | 5/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627659 | 0.83 | CYP11B2 (0.38) | TRPV1CYP11B2NAMPTCCR2SOS1 | |
| SCHEMBL13627657 | 0.81 | TRPV1 (0.38) | TRPV1NAMPTLNPEPDPP7 | |
| SCHEMBL13627582 | 0.79 | KCNH2 (0.50) | NAMPT | |
| SCHEMBL13628373 | 0.77 | CCR2 (0.44) | CCR2 | |
| SCHEMBL13627814 | 0.77 | PPARG (0.41) | NAMPTSOS1DPP7 | |
| SCHEMBL3322750 | 0.76 | CYP11B2 (0.45) | TRPV1CYP11B2 | |
| SCHEMBL20754050 | 0.72 | JAK1 (0.48) | CYP11B2NAMPT | |
| SCHEMBL4153073 | 0.72 | CYP11B2 (0.57) | CYP11B2NAMPTSOS1 | |
| SCHEMBL29579841 | 0.72 | CYP11B2 (0.57) | CYP11B2NAMPTSOS1 | |
| SCHEMBL13407704 | 0.71 | CCR2 (0.52) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618970-B2 | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2009-11-17 | — | — | US | disclosed |