Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627676 | 0.83 | CDK9 (0.37) | TRPV1 | |
| SCHEMBL13627677 | 0.81 | TRPV1 (0.37) | TRPV1DPP7LNPEPNAMPT | |
| SCHEMBL13627814 | 0.78 | PPARG (0.41) | DPP7NAMPT | |
| SCHEMBL13627656 | 0.78 | CCR2 (0.44) | — | |
| SCHEMBL13627582 | 0.77 | KCNH2 (0.50) | NAMPT | |
| SCHEMBL3326632 | 0.76 | TRPV1 (0.43) | TRPV1KCNK3LIMK1LIMK2ABL1 | |
| SCHEMBL4152429 | 0.73 | GRM1 (0.54) | — | |
| SCHEMBL20753966 | 0.73 | JAK1 (0.55) | TRPV1 | |
| SCHEMBL3322631 | 0.71 | CCR2 (0.52) | — | |
| SCHEMBL13741759 | 0.71 | CCR2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618970-B2 | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2009-11-17 | — | — | US | disclosed |