Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA4 | P22459 | 1/20 | 0.34 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.34 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19009022 | 0.83 | — | — | |
| SCHEMBL8567866 | 0.74 | — | — | |
| SCHEMBL6736593 | 0.74 | THRB (0.36) | MAPK1CYP3A4SMN1; SMN2 | |
| SCHEMBL1970312 | 0.74 | KCNA4 (0.39) | KCNA4KCNA1KCNAB1 | |
| SCHEMBL7258460 | 0.72 | KCNA4 (0.43) | KCNA4KCNA1KCNAB1MAPK1SMN1; SMN2 | |
| SCHEMBL42141 | 0.72 | FFAR3 (0.52) | KCNA4KCNA1KCNAB1MAPK1CYP3A4 | |
| SCHEMBL19734618 | 0.71 | ALDH1A1 (0.35) | KCNA4KCNA1KCNAB1CYP3A4 | |
| SCHEMBL21779854 | 0.71 | CYP3A4 (0.32) | MAPK1CYP3A4SMN1; SMN2DRD2 | |
| SCHEMBL23199626 | 0.70 | CETP (0.42) | MAPK1CYP3A4SMN1; SMN2DRD2 | |
| Hydrochloric Acid SCHEMBL15522635 | 0.70 | FFAR3 (0.50) | KCNA4KCNA1KCNAB1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |