Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18776185 | 1.00 | EPHX1 (0.59) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL8403603 | 0.91 | CHRNB2 (0.58) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL10815020 | 0.91 | CHRNB2 (0.58) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL14340134 | 0.87 | TSHR (0.56) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL42937 | 0.86 | — | — | |
| SCHEMBL2819850 | 0.84 | ACHE (0.47) | EPHX1MAPK1SMN1; SMN2ACHEALDH1A1 | |
| SCHEMBL13627734 | 0.84 | TSHR (0.58) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL16541245 | 0.83 | CHRNB2 (0.65) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL24318705 | 0.83 | CHRNB2 (0.50) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL5250584 | 0.83 | CHRNB2 (0.50) | EPHX1CHRNB2CHRNA4CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9387267-B2 | Iodine-containing radial-shaped macromolecular compounds, preparation method thereof and contrast media compositions for CT comprising the same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-07-12 | — | — | US | disclosed |
| US-20130150529-A1 | IODINE-CONTAINING RADIAL-SHAPED MACROMOLECULAR COMPOUNDS, PREPARATION METHOD THEREOF AND CONTRAST MEDIA COMPOSITIONS FOR CT COMPRISING THE SOME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150529-A1 | IODINE-CONTAINING RADIAL-SHAPED MACROMOLECULAR COMPOUNDS, PREPARATION METHOD THEREOF AND CONTRAST MEDIA COMPOSITIONS FOR CT COMPRISING THE SOME | IGFBP1, IGFBP5, IGFBP2 | EPHX1 4117/4885CHRNB2 3277/4885CHRNA4 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.