Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.45 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5635251 | 0.87 | AGTR2 (0.57) | MMP9AGTR2BDKRB2BACE1CTSL | |
| SCHEMBL13979529 | 0.87 | AGTR2 (0.48) | MMP9AGTR2BDKRB2BACE1HRH3 | |
| SCHEMBL5635255 | 0.87 | AGTR2 (0.57) | MMP9AGTR2BDKRB2BACE1CTSL | |
| SCHEMBL6945211 | 0.85 | ABCB1 (0.51) | MMP9AGTR2CYP3A4POLBABCB1 | |
| SCHEMBL15729698 | 0.85 | AGTR2 (0.54) | AGTR2MMP2 | |
| SCHEMBL15729699 | 0.85 | AGTR2 (0.54) | AGTR2MMP2 | |
| SCHEMBL6945215 | 0.85 | ABCB1 (0.51) | MMP9AGTR2CYP3A4POLBABCB1 | |
| SCHEMBL6939235 | 0.81 | POLB (0.51) | LMNACYP3A4SMN1; SMN2POLBPTPN1 | |
| SCHEMBL6939240 | 0.81 | POLB (0.51) | LMNACYP3A4SMN1; SMN2POLBPTPN1 | |
| SCHEMBL15729696 | 0.81 | MC4R (0.41) | AGTR2HRH3PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |