Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.56 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.56 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PHGDH | O43175 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332310 | 0.89 | KMT2A (0.73) | KMT2AMEN1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL6854893 | 0.86 | KMT2A (0.65) | KMT2AMEN1ALDH1A1TP53NPC1 | |
| SCHEMBL28433481 | 0.83 | DDX3X (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL29740651 | 0.82 | KMT2A (0.69) | KMT2AMEN1ALDH1A1TP53NPC1 | |
| SCHEMBL733777 | 0.82 | KMT2A (0.69) | KMT2AMEN1ALDH1A1TP53NPC1 | |
| SCHEMBL6857920 | 0.82 | KMT2A (0.73) | KMT2AMEN1ALDH1A1TP53NPC1 | |
| SCHEMBL13390947 | 0.81 | KMT2A (0.63) | KMT2AMEN1SMN1; SMN2TP53NPC1 | |
| SCHEMBL4388940 | 0.81 | CXCR2 (0.78) | KMT2AMEN1ALDH1A1SMN1; SMN2TP53 | |
| Fluoride SCHEMBL28083677 | 0.81 | KMT2A (0.67) | KMT2AMEN1ALDH1A1TP53NPC1 | |
| SCHEMBL1745798 | 0.80 | KMT2A (0.71) | KMT2AMEN1ALDH1A1TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640462-B2 | Oil gelator | NATIONAL UNIVERSITY CORPORATION SHIZUOKA UNIVERSITY (JP) | 2020-05-05 | — | — | US | disclosed |
| US-10351522-B2 | Sulfonamide derivative and pharmaceutically acceptable acid addition salt thereof | UNIVERSITY OF TSUKUBA (JP) | 2019-07-16 | — | — | US | disclosed |
| US-20180179151-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF | UNIVERSITY OF TSUKUBA (JP) | 2018-06-28 | — | — | US | disclosed |
| US-7612065-B2 | Inhibitors of c-JUN N-terminal kinases (JNK) | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-11-03 | — | — | US | disclosed |
| US-20080033022-A1 | Inhibitors of c-Jun N-terminal kinases (JNK) | SALITURO FRANCESCO G | 2008-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179151-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALT THEREOF | HCRTR2, HCRTR1, NPSR1 | KMT2A 234/4885MEN1 2469/4885ALDH1A1 968/4885 |
| US-10640462-B2 | Oil gelator | MGLL, CCNL2, CCNI | KMT2A 3226/4885MEN1 3185/4885ALDH1A1 593/4885 |
| US-20080033022-A1 | Inhibitors of c-Jun N-terminal kinases (JNK) | MAP3K1, JUN, MAP3K7 | KMT2A 3594/4885MEN1 4320/4885ALDH1A1 4310/4885 |
| US-10351522-B2 | Sulfonamide derivative and pharmaceutically acceptable acid addition salt thereof | HCRTR2, HCRTR1, NPSR1 | KMT2A 234/4885MEN1 2469/4885ALDH1A1 968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.