SCHEMBL1362856

SCHEMBL1362856

CCCN1C(=O)NC(=O)C1S

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.31
TP53 P04637 1/20 0.31
MMP1 P03956 1/20 0.31
MMP9 P14780 1/20 0.31
ABL1 P00519 2/20 0.30
RIN1 Q13671 2/20 0.30
TDP1 Q9NUW8 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1363459 0.88 GAA (0.46) GAATP53MMP1MMP9ABL1
SCHEMBL28178801 0.77 GAA (0.32) GAATP53ABL1RIN1TDP1
SCHEMBL1360935 0.76 MMP1 (0.37) MMP1MMP9
SCHEMBL10547583 0.75 GAA (0.31) GAATP53ABL1RIN1TDP1
SCHEMBL6233396 0.75 KDM4E (0.36) GAATP53ABL1RIN1TDP1
SCHEMBL6233683 0.73 KDM4E (0.33) GAATP53
SCHEMBL6235070 0.72 KDM4E (0.31) GAATP53
SCHEMBL6232620 0.71 ALDH1A1 (0.31) GAA
SCHEMBL1363109 0.70
SCHEMBL1361097 0.67 GAA (0.35) GAATP53ABL1RIN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8066977-B2 Agent for permanent hair waving containing heterocyclic mercapto compound SHOWA DENKO K.K. (JP) 2011-11-29 US disclosed
EP-1883454-B1 AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND SHOWA DENKO KK (JP) 2009-11-04 EP disclosed
US-20090208439-A1 Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound SHOWA DENKO K.K. (JP) 2009-08-20 US disclosed
EP-1883454-A2 AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND Showa Denko K.K. (JP) 2008-02-06 EP disclosed
WO-2006126729-A2 AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND SHOWA DENKO K.K. (JP) 2006-11-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090208439-A1 Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound NSD3, WNT3, MSRB3 GAA 4854/4885TP53 2453/4885MMP1 308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.