Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.40 |
| ▸ | CNR1 | P21554 | 9/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628844 | 0.88 | TP53 (0.37) | TP53LMNAPOLBBAZ2B | |
| SCHEMBL2924408 | 0.82 | CNR2 (0.42) | CNR2CNR1BAZ2B | |
| SCHEMBL13628831 | 0.80 | MCL1 (0.39) | TP53LMNA | |
| SCHEMBL13628841 | 0.79 | TP53 (0.43) | TP53LMNAPOLB | |
| SCHEMBL13628825 | 0.79 | CYP1A2 (0.37) | CNR2CNR1TP53LMNAPOLB | |
| SCHEMBL13628843 | 0.78 | AGTR1 (0.40) | TP53POLB | |
| SCHEMBL13628838 | 0.74 | CYP1A2 (0.36) | CNR2CNR1TP53LMNA | |
| SCHEMBL13628822 | 0.74 | CYP1A2 (0.37) | CNR2CNR1LMNA | |
| SCHEMBL13628864 | 0.74 | CYP1A2 (0.39) | CNR2CNR1LMNA | |
| SCHEMBL13628819 | 0.74 | CNR1 (0.43) | CNR2CNR1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612070-B2 | Heterocyclic compounds as antiinflammatory agents and cyclooxygenase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-11-03 | — | — | US | disclosed |