Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | DLAT | P10515 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30211331 | 0.81 | ALOX5 (0.43) | ALOX5KDM4EMEN1KMT2AAKR1B10 | |
| SCHEMBL316240 | 0.70 | ALOX5 (0.56) | ALOX5KDM4EMEN1KMT2AAKR1B10 | |
| SCHEMBL29358266 | 0.69 | ALOX5 (0.38) | ALOX5KDM4EMEN1KMT2AAKR1B10 | |
| SCHEMBL23178108 | 0.68 | ALOX5 (0.54) | ALOX5KDM4EMEN1KMT2AAKR1B10 | |
| SCHEMBL23044598 | 0.68 | PTGES (0.35) | ALOX5MEN1KMT2APTGES | |
| SCHEMBL13649117 | 0.67 | ALOX5 (0.55) | ALOX5KDM4EMEN1KMT2AAKR1B10 | |
| SCHEMBL31576807 | 0.66 | MEN1 (0.54) | ALOX5KDM4EMEN1KMT2AAKR1B10 | |
| SCHEMBL819253 | 0.66 | ALOX5 (0.78) | ALOX5KDM4EMEN1KMT2AAKR1B10 | |
| SCHEMBL817774 | 0.65 | ALOX5 (0.53) | ALOX5KDM4EMEN1KMT2AAKR1B10 | |
| SCHEMBL23155161 | 0.64 | ALOX5 (0.61) | ALOX5KDM4EMEN1KMT2AAKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286884-A1 | Hops Beta-Acid Anti-Diabetic Composition | Haas, John I. (US) | 2009-11-19 | — | — | US | disclosed |
| US-20090286884-A1 | Hops Beta-Acid Anti-Diabetic Composition | Haas, John I. (US) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286884-A1 | Hops Beta-Acid Anti-Diabetic Composition | GYS2, HBB, HBG2 | ALOX5 2424/4885KDM4E 4830/4885MEN1 2631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.