Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4218029 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AL3MBTL1DPP4 | |
| SCHEMBL4218024 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AL3MBTL1DPP4 | |
| SCHEMBL13615087 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AL3MBTL1DPP4 | |
| SCHEMBL13615077 | 0.90 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AL3MBTL1DPP4 | |
| SCHEMBL13615092 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AL3MBTL1DPP4 | |
| SCHEMBL13629201 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AL3MBTL1DPP4 | |
| SCHEMBL4226804 | 0.82 | SCD5 (0.39) | ALDH1A1MEN1KMT2AL3MBTL1DPP4 | |
| SCHEMBL4226802 | 0.82 | SCD5 (0.39) | ALDH1A1MEN1KMT2AL3MBTL1DPP4 | |
| SCHEMBL13615047 | 0.79 | FAP (0.34) | ALDH1A1MEN1KMT2AL3MBTL1DPP4 | |
| SCHEMBL18815570 | 0.77 | RIPK1 (0.41) | ALDH1A1MEN1KMT2AL3MBTL1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612059-B2 | Pyrrolidine bicyclic compounds and its derivatives, compositions and methods of use | VICURON PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | disclosed |