Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13023901 | 0.74 | MAPK1 (0.41) | CHRNA7MAPK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10800732 | 0.62 | LMNA (0.42) | SLC6A2SLC6A4SLC6A3ALDH1A1KDM4E | |
| SCHEMBL19562787 | 0.62 | LMNA (0.42) | SLC6A2SLC6A4SLC6A3ALDH1A1KDM4E | |
| SCHEMBL27646984 | 0.61 | ALDH1A1 (0.47) | SLC6A2SLC6A4SLC6A3ALDH1A1KDM4E | |
| SCHEMBL18527321 | 0.60 | CHRNA7 (0.48) | CHRNA7SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL16034206 | 0.60 | CHRNA7 (0.48) | CHRNA7SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL18538074 | 0.60 | CHRNA7 (0.48) | CHRNA7SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL18527323 | 0.60 | CHRNA7 (0.48) | CHRNA7SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL9876621 | 0.60 | MAPK1 (0.42) | CHRNA7MAPK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11938948 | 0.59 | RAB9A (0.37) | MAPK1ALDH1A1KDM4EUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318740-B2 | Compounds for protein kinase inhibition | WU ZHANGGUI (US) | 2012-11-27 | — | — | US | disclosed |
| US-20090275585-A1 | Novel Compounds and Therapeutic Use Thereof for Protein Kinase Inhibition | WU ZHANGGUI | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275585-A1 | Novel Compounds and Therapeutic Use Thereof for Protein Kinase Inhibition | CHEK2, CHEK1, PLK1 | CHRNA7 4027/4885MAPK1 532/4885SLC6A2 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.