Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056688 | 0.81 | ALDH1A1 (0.48) | KDM4ERAB9AMAPTNPC1LMNA | |
| SCHEMBL10029581 | 0.78 | KDM4E (0.81) | KDM4ERAB9AMAPTNPC1LMNA | |
| SCHEMBL25873252 | 0.77 | CYP2E1 (0.46) | KDM4ERAB9AMAPTNPC1LMNA | |
| SCHEMBL11263632 | 0.77 | ACHE (0.44) | KDM4EMAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL25872960 | 0.77 | CYP2E1 (0.46) | KDM4ERAB9ANPC1MEN1KMT2A | |
| SCHEMBL16549550 | 0.77 | CYP3A4 (0.50) | KDM4EMAPTLMNAALDH1A1TDP1 | |
| SCHEMBL7453408 | 0.77 | CYP3A4 (0.46) | KDM4ERAB9AMAPTNPC1LMNA | |
| SCHEMBL20156028 | 0.77 | CYP3A4 (0.53) | KDM4ERAB9AMAPTNPC1L3MBTL1 | |
| SCHEMBL8198560 | 0.76 | CYP3A4 (0.60) | KDM4ERAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL2096148 | 0.76 | MAPT (0.61) | KDM4ERAB9AMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3040332-B1 | TETRAZOLINONE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL CO (JP) | 2020-06-03 | — | — | EP | disclosed |
| EP-3040332-B1 | TETRAZOLINONE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL CO (JP) | 2020-06-03 | — | — | EP | disclosed |
| WO-2018138692-A1 | NOVEL FUNGICIDAL CARBAMATE COMPOUNDS | INSECTICIDES (INDIA) LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |
| US-9730448-B2 | Tetrazolinone compound and use of same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |
| US-9730448-B2 | Tetrazolinone compound and use of same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |
| US-9730448-B2 | Tetrazolinone compound and use of same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |
| US-20160205935-A1 | TETRAZOLINONE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-07-21 | — | — | US | disclosed |
| US-20160205935-A1 | TETRAZOLINONE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-07-21 | — | — | US | disclosed |
| US-20160205935-A1 | TETRAZOLINONE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-07-21 | — | — | US | disclosed |
| EP-3040332-A1 | TETRAZOLINONE COMPOUND AND USE OF SAME | Sumitomo Chemical Company, Limited (JP) | 2016-07-06 | — | — | EP | disclosed |
| EP-3040332-A1 | TETRAZOLINONE COMPOUND AND USE OF SAME | Sumitomo Chemical Company, Limited (JP) | 2016-07-06 | — | — | EP | disclosed |
| WO-2015030217-A1 | TETRAZOLINONE COMPOUND AND USE OF SAME | 住友化学株式会社 (JP) | 2015-03-05 | — | — | WO | disclosed |
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160205935-A1 | TETRAZOLINONE COMPOUND AND USE OF SAME | MT-CO1, UQCRB, RPS20 | KDM4E 3329/4885RAB9A 475/4885MAPT 3897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.