Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13629598 | 0.81 | PTGS2 (0.41) | KDM4ECYP1A2CYP2C9LMNANTRK1 | |
| SCHEMBL310305 | 0.76 | TACR1 (0.44) | KDM4EALDH1A1HPGD | |
| SCHEMBL3385723 | 0.73 | PTGS2 (0.49) | KDM4EALDH1A1TSHRCYP1A2CYP2C9 | |
| SCHEMBL27606848 | 0.72 | ALDH1A1 (0.44) | KDM4EALDH1A1TSHRTDP1HPGD | |
| SCHEMBL7120569 | 0.70 | MAPT (0.50) | KDM4EALDH1A1TSHRTDP1HPGD | |
| SCHEMBL1186123 | 0.70 | ALDH1A1 (0.50) | KDM4EALDH1A1TSHRTDP1TUBB1 | |
| SCHEMBL4205532 | 0.69 | ATM (0.45) | KDM4EALDH1A1TSHRTDP1HPGD | |
| SCHEMBL7051253 | 0.69 | ALDH1A1 (0.44) | KDM4EALDH1A1TSHRTDP1TUBB1 | |
| SCHEMBL5193938 | 0.69 | ALDH1A1 (0.42) | KDM4EALDH1A1TSHRTDP1TUBB1 | |
| SCHEMBL8533478 | 0.69 | LMNA (0.42) | ALDH1A1TSHRHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |