Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10063570 | 1.00 | KDM4E (0.44) | KDM4EL3MBTL1ATMPGRLMNA | |
| SCHEMBL20664591 | 0.87 | KDM4E (0.41) | KDM4EL3MBTL1ATMPGRLMNA | |
| SCHEMBL3787566 | 0.86 | KDM4E (0.48) | KDM4EL3MBTL1ATMPGRLMNA | |
| SCHEMBL1201083 | 0.86 | KDM4E (0.48) | KDM4EL3MBTL1ATMPGRLMNA | |
| SCHEMBL23126776 | 0.85 | KDM4E (0.46) | KDM4EL3MBTL1ATMPGRLMNA | |
| SCHEMBL15306472 | 0.83 | PGR (0.38) | KDM4EL3MBTL1ATMPGRLMNA | |
| SCHEMBL13629284 | 0.83 | RORA (0.45) | KDM4EL3MBTL1ATMPGRLMNA | |
| SCHEMBL31419534 | 0.83 | KDM4E (0.53) | KDM4EL3MBTL1ATMPGRLMNA | |
| SCHEMBL3810170 | 0.83 | KDM4E (0.53) | KDM4EL3MBTL1ATMPGRLMNA | |
| SCHEMBL29435321 | 0.82 | KDM4E (0.64) | KDM4EL3MBTL1ATMPGRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8343636-B2 | Crosslinkable hole-transporting materials for organic light-emitting devices | UNIVERSITY OF WASHINGTON (US) | 2013-01-01 | — | — | US | disclosed |
| US-20090278445-A1 | CROSSLINKABLE HOLE-TRANSPORTING MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES | WASHINGTON, UNIVERSITY OF (US) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090278445-A1 | CROSSLINKABLE HOLE-TRANSPORTING MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES | SUN2, HTT, SLC29A1 | KDM4E 3636/4885L3MBTL1 714/4885ATM 2875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.