Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13630907 | 0.83 | HDAC6 (0.36) | HDAC6TSHR | |
| SCHEMBL13630893 | 0.80 | POLB (0.61) | ALDH1A1POLBKDM4EHSD17B10GAA | |
| SCHEMBL1161078 | 0.72 | NR5A2 (0.42) | ALDH1A1POLBHDAC6KDM4EL3MBTL1 | |
| SCHEMBL10092236 | 0.71 | TSHR (0.57) | RECQLALDH1A1POLBKDM4EHSD17B10 | |
| SCHEMBL13630898 | 0.69 | TSHR (0.50) | RECQLALDH1A1POLBKDM4ETSHR | |
| SCHEMBL13630894 | 0.69 | TSHR (0.50) | RECQLALDH1A1POLBKDM4EHSD17B10 | |
| SCHEMBL26200750 | 0.69 | TSHR (0.53) | RECQLALDH1A1POLBKDM4EHSD17B10 | |
| SCHEMBL13630895 | 0.67 | TSHR (0.52) | RECQLALDH1A1POLBKDM4ETSHR | |
| SCHEMBL30914516 | 0.67 | ALDH1A1 (0.83) | RECQLALDH1A1POLBHDAC6KDM4E | |
| SCHEMBL18997736 | 0.67 | TSHR (0.50) | RECQLALDH1A1POLBTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |