Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13630908 | 0.83 | RECQL (0.47) | HDAC6TSHR | |
| SCHEMBL1161078 | 0.68 | NR5A2 (0.42) | HDAC6HTT | |
| SCHEMBL3941432 | 0.68 | CES2 (0.39) | TSHRSLC6A3HTT | |
| SCHEMBL22938122 | 0.68 | CES2 (0.39) | HDAC6SLC6A3HTT | |
| SCHEMBL3941437 | 0.68 | CES2 (0.39) | TSHRSLC6A3HTT | |
| SCHEMBL31194929 | 0.68 | ALDH1A1 (0.58) | EPHX1MTNR1A | |
| SCHEMBL4151018 | 0.67 | CNR2 (0.40) | TSHRCYP3A4HTT | |
| SCHEMBL4151017 | 0.67 | CNR2 (0.40) | TSHRCYP3A4HTT | |
| SCHEMBL3190326 | 0.66 | EPHX1 (0.61) | EPHX1TSHR | |
| SCHEMBL3180074 | 0.65 | ALOX5 (0.39) | HDAC6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |