Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.62 |
| ▸ | PAM | P19021 | 2/20 | 0.60 |
| ▸ | TOP1 | P11387 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798110 | 1.00 | TBXAS1 (0.62) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL2379927 | 1.00 | TBXAS1 (0.62) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL850919 | 0.94 | TBXAS1 (0.69) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL850920 | 0.94 | TBXAS1 (0.69) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL849353 | 0.93 | TBXAS1 (0.68) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL8093646 | 0.93 | TBXAS1 (0.68) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL5176079 | 0.93 | TBXAS1 (0.68) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL849354 | 0.93 | TBXAS1 (0.68) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL9303907 | 0.93 | TBXAS1 (0.68) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL11606213 | 0.93 | TBXAS1 (0.68) | TBXAS1PAMTOP1ALDH1A1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026280-B2 | For therapy of cancer, hematological disorders, e.g., hemoglobinopathies, and genetic related metabolic disorders, e.g., cystic fibrosis and adrenoleukodystrophy. | ERRANT GENE THERAPEUTICS, LLC (US) | 2011-09-27 | — | — | US | claimed |
| EP-1566996-B1 | METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT | MONSANTO TECHNOLOGY LLC (US) | 2009-11-11 | — | — | EP | claimed |
| US-20240374689-A1 | HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME | LONGEVITY BIOTECH, INC. | 2024-11-14 | — | — | US | disclosed |
| US-20230080520-A1 | PEPTIDES COMPRISING NON-NATURAL AMINO ACIDS AND METHODS OF MAKING AND USING THE SAME | LONGEVITY BIOTECH, INC. | 2023-03-16 | — | — | US | disclosed |
| US-11604185-B2 | Methods for detection of botulinum neurotoxin | CITY OF HOPE (US) | 2023-03-14 | — | — | US | disclosed |
| US-11278595-B2 | Peptides comprising non-natural amino acids and methods of making and using the same | LONGEVITY BIOTECH, INC. (US) | 2022-03-22 | — | — | US | disclosed |
| US-20210255174-A1 | METHODS FOR DETECTION OF BOTULINUM NEUROTOXIN | CITY OF HOPE (US) | 2021-08-19 | — | — | US | disclosed |
| US-20210205415-A1 | HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME | LONGEVITY BIOTECH, INC | 2021-07-08 | — | — | US | disclosed |
| US-20200384085-A1 | PEPTIDES COMPRISING NON-NATURAL AMINO ACIDS AND METHODS OF MAKING AND USING THE SAME | LONGEVITY BIOTECH, INC. | 2020-12-10 | — | — | US | disclosed |
| US-10775366-B2 | Substrates for detection of botulinum neurotoxin | CITY OF HOPE (US) | 2020-09-15 | — | — | US | disclosed |
| US-10772934-B2 | Highly active polypeptides and methods of making and using the same | LONGEVITY BIOTECH, INC. (US) | 2020-09-15 | — | — | US | disclosed |
| EP-0807114-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0509857-B1 | Alpha-methylene 5-thiazolo acetic acid derivatives, intermediates and process of preparation, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1996-02-28 | — | — | EP | disclosed |
| EP-0509857-A1 | Alpha-methylene 5-thiazolo acetic acid derivatives, intermediates and process of preparation, their use as fungicides and compositions containing them | ROUSSEL UCLAF (FR) | 1992-10-21 | — | — | EP | disclosed |
| EP-0123543-B1 | LEUKOTRIENE ANTAGONISTS, THEIR PRODUCTION AND USE AND COMPOSITIONS CONTAINING THEM | MERCK FROSST CANADA INC. (CA) | 1988-02-03 | — | — | EP | disclosed |
| US-4609744-A | 4-oxo-benzopyran carboxylic acids | MERCK FROSST CANADA INC. (CA) | 1986-09-02 | — | — | US | disclosed |
| US-4513005-A | SULFIDE OR SULFONE HYDROXY ACIDS | LILLY INDUSTRIES LIMITED (GB) | 1985-04-23 | — | — | US | disclosed |
| EP-0068739-B1 | SULPHUR-CONTAINING 5-HYDROXY-ALKANOIC ACID DERIVATIVES, THEIR USE AS PHARMACEUTICAL PREPARATIONS AND PROCESS FOR THEIR PRODUCTION | Lilly Industries Limited (GB) | 1984-11-14 | — | — | EP | disclosed |
| EP-0123543-A1 | Leukotriene antagonists, their production and use and compositions containing them | MERCK FROSST CANADA INC. (CA) | 1984-10-31 | — | — | EP | disclosed |
| EP-0068739-A1 | Sulphur-containing 5-hydroxy-alkanoic acid derivatives, their use as pharmaceutical preparations and process for their production | Lilly Industries Limited (GB) | 1983-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11604185-B2 | Methods for detection of botulinum neurotoxin | ANTXR2, INHA, PRSS12 | TBXAS1 479/4885PAM 1998/4885TOP1 2811/4885 |
| US-20200384085-A1 | PEPTIDES COMPRISING NON-NATURAL AMINO ACIDS AND METHODS OF MAKING AND USING THE SAME | APLNR, SCTR, GIPR | TBXAS1 1589/4885PAM 983/4885TOP1 4865/4885 |
| US-20230080520-A1 | PEPTIDES COMPRISING NON-NATURAL AMINO ACIDS AND METHODS OF MAKING AND USING THE SAME | APLNR, SCTR, GIPR | TBXAS1 1589/4885PAM 983/4885TOP1 4865/4885 |
| US-20210255174-A1 | METHODS FOR DETECTION OF BOTULINUM NEUROTOXIN | ANTXR2, INHA, PRSS12 | TBXAS1 479/4885PAM 1998/4885TOP1 2811/4885 |
| US-10775366-B2 | Substrates for detection of botulinum neurotoxin | ANTXR2, INHA, PRSS12 | TBXAS1 486/4885PAM 1977/4885TOP1 2934/4885 |
| US-11278595-B2 | Peptides comprising non-natural amino acids and methods of making and using the same | APLNR, SCTR, GIPR | TBXAS1 1589/4885PAM 983/4885TOP1 4865/4885 |
| US-20210205415-A1 | HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME | SCTR, GIPR, APLNR | TBXAS1 1665/4885PAM 1091/4885TOP1 4808/4885 |
| US-10772934-B2 | Highly active polypeptides and methods of making and using the same | SCTR, GIPR, APLNR | TBXAS1 1665/4885PAM 1091/4885TOP1 4808/4885 |
| US-20240374689-A1 | HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME | SCTR, GIPR, APLNR | TBXAS1 1665/4885PAM 1091/4885TOP1 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.