Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.62 |
| ▸ | PAM | P19021 | 2/20 | 0.60 |
| ▸ | TOP1 | P11387 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1363095 | 1.00 | TBXAS1 (0.62) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL8798110 | 1.00 | TBXAS1 (0.62) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL850919 | 0.94 | TBXAS1 (0.69) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL850920 | 0.94 | TBXAS1 (0.69) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL849353 | 0.93 | TBXAS1 (0.68) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL8093646 | 0.93 | TBXAS1 (0.68) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL5176079 | 0.93 | TBXAS1 (0.68) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL849354 | 0.93 | TBXAS1 (0.68) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL9303907 | 0.93 | TBXAS1 (0.68) | TBXAS1PAMTOP1ALDH1A1PPARA | |
| SCHEMBL11606213 | 0.93 | TBXAS1 (0.68) | TBXAS1PAMTOP1ALDH1A1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026280-B2 | For therapy of cancer, hematological disorders, e.g., hemoglobinopathies, and genetic related metabolic disorders, e.g., cystic fibrosis and adrenoleukodystrophy. | ERRANT GENE THERAPEUTICS, LLC (US) | 2011-09-27 | — | — | US | claimed |
| US-7259135-B2 | Use of hexenal derivatives as perfumes | KAO CORPORATION (JP) | 2007-08-21 | — | — | US | claimed |
| US-20240374689-A1 | HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME | LONGEVITY BIOTECH, INC. | 2024-11-14 | — | — | US | disclosed |
| US-11998901-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | INSTITUTE FOR BASIC SCIENCE (KR) | 2024-06-04 | — | — | US | disclosed |
| CN-111566116-B | Novel metal complex, process for producing the same, and process for producing gamma-lactam compound using the same | 基础科学研究院 | 2023-06-09 | — | — | CN | disclosed |
| US-20230080520-A1 | PEPTIDES COMPRISING NON-NATURAL AMINO ACIDS AND METHODS OF MAKING AND USING THE SAME | LONGEVITY BIOTECH, INC. | 2023-03-16 | — | — | US | disclosed |
| US-20220168717-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | INSTITUTE FOR BASIC SCIENCE (KR) | 2022-06-02 | — | — | US | disclosed |
| US-11344872-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | INSTITUTE FOR BASIC SCIENCE (KR) | 2022-05-31 | — | — | US | disclosed |
| US-11278595-B2 | Peptides comprising non-natural amino acids and methods of making and using the same | LONGEVITY BIOTECH, INC. (US) | 2022-03-22 | — | — | US | disclosed |
| US-20210205415-A1 | HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME | LONGEVITY BIOTECH, INC | 2021-07-08 | — | — | US | disclosed |
| US-20200384085-A1 | PEPTIDES COMPRISING NON-NATURAL AMINO ACIDS AND METHODS OF MAKING AND USING THE SAME | LONGEVITY BIOTECH, INC. | 2020-12-10 | — | — | US | disclosed |
| EP-1600151-A1 | Perfume particles and a process for preparing the same | Kao Corporation (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-20050227908-A1 | Ether lactone | KAO CORPORATION (JP) | 2005-10-13 | — | — | US | disclosed |
| US-20050130875-A1 | Use of hexenal derivates as perfumes | KAO CORPORATION (JP) | 2005-06-16 | — | — | US | disclosed |
| US-20050119158-A1 | Use of unsaturated ketones as a perfume | PROVIDENT BANK | 2005-06-02 | — | — | US | disclosed |
| US-20040162447-A1 | 2-methyl-4-ethyl-2-octene-1-aldehyde | MARKERT THOMAS (DE) | 2004-08-19 | — | — | US | disclosed |
| US-20040138092-A1 | 2,3, 5, 5-tetramethylhexanal derivatives | KAO CORPORATION (JP) | 2004-07-15 | — | — | US | disclosed |
| US-4513005-A | SULFIDE OR SULFONE HYDROXY ACIDS | LILLY INDUSTRIES LIMITED (GB) | 1985-04-23 | — | — | US | disclosed |
| EP-0068739-B1 | SULPHUR-CONTAINING 5-HYDROXY-ALKANOIC ACID DERIVATIVES, THEIR USE AS PHARMACEUTICAL PREPARATIONS AND PROCESS FOR THEIR PRODUCTION | Lilly Industries Limited (GB) | 1984-11-14 | — | — | EP | disclosed |
| EP-0068739-A1 | Sulphur-containing 5-hydroxy-alkanoic acid derivatives, their use as pharmaceutical preparations and process for their production | Lilly Industries Limited (GB) | 1983-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138092-A1 | 2,3, 5, 5-tetramethylhexanal derivatives | ADH5, TREH, CFH | TBXAS1 538/4885PAM 3653/4885TOP1 1706/4885 |
| US-20200384085-A1 | PEPTIDES COMPRISING NON-NATURAL AMINO ACIDS AND METHODS OF MAKING AND USING THE SAME | APLNR, SCTR, GIPR | TBXAS1 1589/4885PAM 983/4885TOP1 4865/4885 |
| US-20220168717-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | COASY, NOTUM, MRPL21 | TBXAS1 2549/4885PAM 692/4885TOP1 205/4885 |
| US-20050227908-A1 | Ether lactone | CYP51A1, ADH5, HSD17B14 | TBXAS1 1669/4885PAM 2657/4885TOP1 3618/4885 |
| US-20050119158-A1 | Use of unsaturated ketones as a perfume | FAAH, FAAH2, FASN | TBXAS1 1183/4885PAM 1827/4885TOP1 4102/4885 |
| US-20230080520-A1 | PEPTIDES COMPRISING NON-NATURAL AMINO ACIDS AND METHODS OF MAKING AND USING THE SAME | APLNR, SCTR, GIPR | TBXAS1 1589/4885PAM 983/4885TOP1 4865/4885 |
| US-11344872-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | COASY, NOTUM, MRPL21 | TBXAS1 2539/4885PAM 604/4885TOP1 97/4885 |
| US-11278595-B2 | Peptides comprising non-natural amino acids and methods of making and using the same | APLNR, SCTR, GIPR | TBXAS1 1589/4885PAM 983/4885TOP1 4865/4885 |
| US-20040162447-A1 | 2-methyl-4-ethyl-2-octene-1-aldehyde | ADH1A, ALDH1A1, ADH5 | TBXAS1 2478/4885PAM 3060/4885TOP1 1233/4885 |
| US-20210205415-A1 | HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME | SCTR, GIPR, APLNR | TBXAS1 1665/4885PAM 1091/4885TOP1 4808/4885 |
| US-11998901-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | COASY, NOTUM, MRPL21 | TBXAS1 2539/4885PAM 604/4885TOP1 97/4885 |
| US-20050130875-A1 | Use of hexenal derivates as perfumes | ADH1C, ADH5, ZDHHC2 | TBXAS1 2112/4885PAM 860/4885TOP1 2249/4885 |
| US-20240374689-A1 | HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME | SCTR, GIPR, APLNR | TBXAS1 1665/4885PAM 1091/4885TOP1 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.