Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434264 | 1.00 | SIGMAR1 (0.42) | SIGMAR1ALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL5987218 | 1.00 | SIGMAR1 (0.42) | SIGMAR1ALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL13434259 | 1.00 | SIGMAR1 (0.42) | SIGMAR1ALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL7602474 | 0.88 | HPGD (0.44) | SIGMAR1ALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL2820441 | 0.86 | SIGMAR1 (0.47) | SIGMAR1KDM4E | |
| SCHEMBL3487365 | 0.86 | SIGMAR1 (0.47) | SIGMAR1KDM4E | |
| SCHEMBL2820438 | 0.86 | SIGMAR1 (0.47) | SIGMAR1KDM4E | |
| SCHEMBL13434260 | 0.82 | ALDH1A1 (0.41) | SIGMAR1ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL12361787 | 0.82 | ALDH1A1 (0.41) | SIGMAR1ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL13630926 | 0.82 | ALDH1A1 (0.41) | SIGMAR1ALDH1A1L3MBTL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |