Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13631024 | 1.00 | SIGMAR1 (0.42) | SIGMAR1ALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL5987218 | 1.00 | SIGMAR1 (0.42) | SIGMAR1ALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL13434259 | 1.00 | SIGMAR1 (0.42) | SIGMAR1ALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL7602474 | 0.88 | HPGD (0.44) | SIGMAR1ALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL2820441 | 0.86 | SIGMAR1 (0.47) | SIGMAR1KDM4E | |
| SCHEMBL3487365 | 0.86 | SIGMAR1 (0.47) | SIGMAR1KDM4E | |
| SCHEMBL2820438 | 0.86 | SIGMAR1 (0.47) | SIGMAR1KDM4E | |
| SCHEMBL13434260 | 0.82 | ALDH1A1 (0.41) | SIGMAR1ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL12361787 | 0.82 | ALDH1A1 (0.41) | SIGMAR1ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL13630926 | 0.82 | ALDH1A1 (0.41) | SIGMAR1ALDH1A1L3MBTL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056497-A1 | AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056497-A1 | AMIDE DERIVATIVE | REN, AGTR1, AGTR2 | SIGMAR1 570/4885ALDH1A1 348/4885L3MBTL1 3531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.