Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.37 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31005446 | 0.85 | ALDH1A1 (0.43) | HDAC1HDAC2LMNAALDH1A1EHMT2 | |
| SCHEMBL1120030 | 0.85 | ALDH1A1 (0.43) | HDAC1HDAC2LMNAALDH1A1EHMT2 | |
| SCHEMBL4348222 | 0.82 | HDAC1 (0.39) | HDAC1HDAC2LMNAALDH1A1EHMT2 | |
| SCHEMBL31005440 | 0.82 | HDAC1 (0.39) | HDAC1HDAC2LMNAALDH1A1EHMT2 | |
| SCHEMBL19188392 | 0.76 | HDAC1 (0.37) | HDAC1HDAC2LMNAALDH1A1MAPT | |
| SCHEMBL10340548 | 0.73 | LMNA (0.50) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL25413645 | 0.73 | ALDH1A1 (0.47) | HDAC1HDAC2ALDH1A1EHMT2EHMT1 | |
| SCHEMBL10086909 | 0.73 | ALDH1A1 (0.47) | HDAC1HDAC2LMNAALDH1A1EHMT2 | |
| SCHEMBL25413647 | 0.73 | ALDH1A1 (0.47) | HDAC1HDAC2ALDH1A1EHMT2EHMT1 | |
| SCHEMBL20095020 | 0.72 | LMNA (0.45) | HDAC1HDAC2LMNAALDH1A1EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134977-A1 | CROSS-LINKERS AND THEIR USES | IMMUNOGEN, INC. (US) | 2009-11-05 | — | — | WO | disclosed |