Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22279584 | 0.86 | RAB9A (0.65) | RAB9ANPC1MAPK1KMT2AKDM4E | |
| SCHEMBL6223693 | 0.86 | MAPK1 (0.63) | RAB9ANPC1MAPK1KMT2AKDM4E | |
| SCHEMBL12928392 | 0.86 | MAPK1 (0.63) | RAB9ANPC1MAPK1KMT2AKDM4E | |
| SCHEMBL19723638 | 0.85 | RAB9A (0.58) | RAB9ANPC1MAPK1KMT2AKDM4E | |
| SCHEMBL13827004 | 0.83 | MAPK1 (0.60) | RAB9ANPC1MAPK1KMT2AKDM4E | |
| SCHEMBL18801119 | 0.82 | MAPK1 (0.59) | RAB9ANPC1MAPK1KMT2AKDM4E | |
| SCHEMBL12295460 | 0.82 | MAPK1 (0.66) | RAB9ANPC1MAPK1KMT2AKDM4E | |
| SCHEMBL19723665 | 0.81 | NPC1 (1.00) | RAB9ANPC1MAPK1KMT2AKDM4E | |
| SCHEMBL19723692 | 0.81 | RAB9A (0.48) | RAB9ANPC1MAPK1KMT2AKDM4E | |
| SCHEMBL10242673 | 0.80 | KMT2A (0.61) | RAB9ANPC1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210009583-A1 | DEUTERATED IMIDAZOPYRIDINES | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-01-14 | — | — | US | disclosed |
| WO-2019175737-A1 | DEUTERATED IMIDAZOPYRIDINES | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2019-09-19 | — | — | WO | disclosed |
| US-7615639-B2 | 1-pyridyl-benzofuro[3,2-b]pyridin-2(1H)-ones | TIBOTEC PHARMACEUTICALS, LTD. (IE) | 2009-11-10 | — | — | US | disclosed |
| US-20070265295-A1 | 1-Heterocyclyl-1,5-Dihydro-Pyrido[3,2-B]Indol-2-Ones | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265295-A1 | 1-Heterocyclyl-1,5-Dihydro-Pyrido[3,2-B]Indol-2-Ones | CBR1, HRH4, CYP4B1 | RAB9A 3284/4885NPC1 1013/4885MAPK1 2120/4885 |
| US-20210009583-A1 | DEUTERATED IMIDAZOPYRIDINES | SDHA, PDF, IDH2 | RAB9A 2939/4885NPC1 3736/4885MAPK1 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.