Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | COMT | P21964 | 1/20 | 0.44 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2931119 | 0.86 | ALDH1A1 (0.54) | KMT2AALDH1A1KDM4EGAAHTT | |
| SCHEMBL3283016 | 0.85 | TGFBR1 (0.55) | KMT2AALDH1A1KDM4EGAAHTT | |
| SCHEMBL4256814 | 0.83 | KMT2A (0.58) | KMT2AALDH1A1KDM4EGAAHTT | |
| SCHEMBL15445014 | 0.83 | RAB9A (0.46) | KMT2AALDH1A1KDM4EGAAHTT | |
| SCHEMBL6112913 | 0.83 | ALDH1A1 (0.69) | KMT2AALDH1A1GAAPOLBRAB9A | |
| SCHEMBL4794691 | 0.81 | KMT2A (0.55) | KMT2AALDH1A1KDM4EGAAHTT | |
| SCHEMBL6012095 | 0.81 | RAB9A (0.59) | ALDH1A1KDM4EGAAMAPTLMNA | |
| SCHEMBL10514161 | 0.81 | ALDH1A1 (0.74) | KMT2AALDH1A1KDM4EGAAHTT | |
| SCHEMBL4531748 | 0.80 | KMT2A (0.54) | KMT2AALDH1A1KDM4EGAAPOLB | |
| SCHEMBL13633334 | 0.80 | RAB9A (0.68) | KMT2AALDH1A1KDM4EGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9908876-B2 | Imidazo [1,2-a]pyridine compounds, synthesis thereof, and methods of using same | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2018-03-06 | — | — | US | disclosed |
| US-8148373-B2 | Compounds | ASTRAZENECA AB (SE) | 2012-04-03 | — | — | US | disclosed |
| US-20090298807-A1 | Compounds | ASTRAZENECA AB (SE) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298807-A1 | Compounds | PKD1, SLC10A1, ABCB11 | KMT2A 4286/4885ALDH1A1 102/4885KDM4E 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.