SCHEMBL1363368

SCHEMBL1363368

C=C(C)c1ccc(CC)cc1CC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.42
HSD17B1 P14061 1/20 0.40
AKT1 P31749 1/20 0.39
BACE1 P56817 1/20 0.38
ALDH1A1 P00352 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
MAPK1 P28482 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
AKR1C3 P42330 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7932090 0.87 HSD17B1 (0.37) TRPA1HSD17B1AKT1BACE1LMNA
SCHEMBL15524468 0.84 TRPA1 (0.42) TRPA1AKT1BACE1ALDH1A1CYP1A2
SCHEMBL18244044 0.83 TRPA1 (0.45) TRPA1HSD17B1AKT1BACE1ALDH1A1
SCHEMBL29827550 0.82 HSD17B1 (0.58) TRPA1HSD17B1AKT1BACE1ALDH1A1
SCHEMBL20262941 0.82 HSD17B1 (0.41) HSD17B1ALDH1A1KMT2AMEN1HPGD
SCHEMBL29483331 0.82 HSD17B1 (0.41) HSD17B1ALDH1A1KMT2AMEN1HPGD
SCHEMBL3737547 0.82 HSD17B1 (0.58) TRPA1HSD17B1AKT1BACE1ALDH1A1
SCHEMBL25988701 0.81 MAPT (0.40) TRPA1AKT1ALDH1A1CYP1A2LMNA
SCHEMBL20194348 0.80 HSD17B1 (0.33) HSD17B1BACE1ALDH1A1MAPTRAB9A
SCHEMBL19415763 0.80 TRPA1 (0.42) TRPA1ALDH1A1CYP1A2CYP2A6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4306111-A2 3-(5-HYDROXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF Novartis AG (CH) 2024-01-17 EP disclosed
EP-3820573-B1 3-(5-HYDROXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF IKAROS FAMILY ZINC FINGER 2 (IKZF2)-DEPENDENT DISEASES NOVARTIS AG (CH) 2023-08-09 EP disclosed
CN-105745581-B Negatively charged toner and its manufacturing method 日本瑞翁株式会社 2019-10-08 CN disclosed
CN-106133615-B Toner group 日本瑞翁株式会社 2019-10-08 CN disclosed
US-10353306-B2 Method for producing negatively chargeable toner, and negatively chargeable toner ZEON CORPORATION (JP) 2019-07-16 US disclosed
US-20190041764-A1 POSITIVELY-CHARGEABLE BLACK TONER ZEON CORPORATION (JP) 2019-02-07 US disclosed
US-10175594-B2 Toner set ZEON CORPORATION (JP) 2019-01-08 US disclosed
US-20180224762-A1 TONER SET ZEON CORPORATION (JP) 2018-08-09 US disclosed
US-9958798-B2 Toner set ZEON CORPORATION (JP) 2018-05-01 US disclosed
US-20180107127-A1 METHOD FOR PRODUCING NEGATIVELY CHARGEABLE TONER, AND NEGATIVELY CHARGEABLE TONER ZEON CORPORATION (JP) 2018-04-19 US disclosed
US-20150025213-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-01-22 US disclosed
US-8883946-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-11-11 US disclosed
US-20140080989-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-03-20 US disclosed
US-8067140-B2 reduced residual amount of a decomposed product of a polymerization initiator and an unreacted polymerizable monomer (mainly styrene), less odor produced upon fixing so as to avoid deteriorating surrounding environment, an excellent shelf stability at high temperature upon storing or anti-blocking ZEON CORPORATION (JP) 2011-11-29 US disclosed
US-20080182189-A1 reduced residual amount of a decomposed product of a polymerization initiator and an unreacted polymerizable monomer (mainly styrene), less odor produced upon fixing so as to avoid deteriorating surrounding environment, an excellent shelf stability at high temperature upon storing or anti-blocking ZEON CORPORATION (JP) 2008-07-31 US disclosed
EP-1273976-B1 TONER FOR ELECTROSTATIC IMAGE DEVELOPMENT AND PROCESS FOR PRODUCING THE SAME ZEON CORP (JP) 2007-10-03 EP disclosed
US-6887637-B2 Toner for electrostatic image development and process for producing the same ZEON CORPORATION (JP) 2005-05-03 US disclosed
US-20030027070-A1 Toner for electrostatic image development and process for producing the same ZEON CORPORATION (JP) 2003-02-06 US disclosed
EP-1273976-A1 TONER FOR ELECTROSTATIC IMAGE DEVELOPMENT AND PROCESS FOR PRODUCING THE SAME Zeon Corporation (JP) 2003-01-08 EP disclosed
US-6342328-B1 BINDER RESIN, COLOR AND CHARGE CONTROL AGENT NIPPON ZEON CO., LTD. (JP) 2002-01-29 US disclosed