Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1363368 | 0.87 | TRPA1 (0.42) | HSD17B1AKT1BACE1KMT2ATRPA1 | |
| SCHEMBL29220434 | 0.80 | GABRP (0.38) | HSD17B1AKT1BACE1KMT2ARXRA | |
| SCHEMBL20156583 | 0.78 | FLT1 (0.49) | HSD17B1FLT1FLT4KDRKMT2A | |
| SCHEMBL29483331 | 0.77 | HSD17B1 (0.41) | HSD17B1KMT2AHTTRXRA | |
| SCHEMBL20262941 | 0.77 | HSD17B1 (0.41) | HSD17B1KMT2AHTTRXRA | |
| SCHEMBL20194348 | 0.76 | HSD17B1 (0.33) | HSD17B1BACE1KMT2AMAPTHTT | |
| SCHEMBL27005987 | 0.76 | HSD17B1 (0.40) | HSD17B1CSNK2A1KMT2AMAPTHTT | |
| SCHEMBL7909295 | 0.76 | HSD17B1 (0.51) | HSD17B1CA1CA2KDM4EHTT | |
| SCHEMBL606254 | 0.74 | DHFR (0.42) | AKT1BACE1CA1CA2CSNK2A2 | |
| Acrylamide SCHEMBL29220423 | 0.73 | GABRP (0.38) | BACE1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245862-B1 | GOLF BALL COMPRISING COVER AND CORE LAYER, WHEREIN COVER IS FORMED OF COMPOSITION CONSISTING ESSENTIALLY OF AT LEAST ONE IONOMER FORMED FROM THERMOPLASTIC POLYMER HAVING SULFONATE AND/OR PHOSPHONATE MOIETIES | ACUSHNET COMPANY | 2001-06-12 | — | — | US | disclosed |
| WO-1999061113-A1 | GOLF BALLS COMPRISING SULFONATED OR PHOSPHONATED IONOMERS | ACUSHNET COMPANY (US) | 1999-12-02 | — | — | WO | disclosed |