Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13503414 | 0.83 | TARBP2 (0.53) | KDM4ERAB9APOLBMAPTSMN1; SMN2 | |
| SCHEMBL9097470 | 0.80 | ESR1 (0.50) | KDM4ERAB9APOLBMAPTSMN1; SMN2 | |
| SCHEMBL13179907 | 0.80 | HSD17B10 (0.58) | KDM4ERAB9APOLBMAPTSMN1; SMN2 | |
| SCHEMBL12961041 | 0.80 | ALDH1A1 (0.52) | KDM4ERAB9APOLBMAPTNPSR1 | |
| SCHEMBL266619 | 0.80 | KDM4E (0.66) | KDM4ERAB9APPARGPPARAKMT2A | |
| SCHEMBL13633897 | 0.79 | KDM4E (0.57) | KDM4ERAB9APOLBMAPTSMN1; SMN2 | |
| SCHEMBL6511253 | 0.77 | KDM4E (0.60) | KDM4ERAB9APOLBMAPTSMN1; SMN2 | |
| SCHEMBL4359109 | 0.77 | KDM4E (0.56) | KDM4ERAB9APOLBMAPTSMN1; SMN2 | |
| SCHEMBL20861471 | 0.76 | PPARA (0.53) | KDM4ERAB9AMAPTPPARGPPARA | |
| SCHEMBL5365528 | 0.75 | KDM4E (0.57) | KDM4ERAB9APOLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275565-A1 | Substituted aralkyl derivatives | CADILA HEALTHCARE LIMITED (IN) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275565-A1 | Substituted aralkyl derivatives | UGT1A7, UGT1A10, UGT2B7 | KDM4E 4614/4885RAB9A 543/4885POLB 3020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.