Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634261 | 0.93 | SIRT6 (0.51) | SIRT6KDM4EALDH1A1RECQLLMNA | |
| SCHEMBL13163912 | 0.88 | SIRT6 (0.48) | SIRT6KDM4EALDH1A1RECQLLMNA | |
| SCHEMBL13163915 | 0.87 | ALDH1A1 (0.61) | SIRT6KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL15888503 | 0.86 | SIRT6 (0.50) | SIRT6KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL13162333 | 0.84 | SIRT6 (0.47) | SIRT6KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL13634150 | 0.84 | SIRT6 (0.55) | SIRT6KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL495726 | 0.83 | SIRT6 (0.54) | SIRT6KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL13162347 | 0.82 | SIRT6 (0.50) | SIRT6KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL378383 | 0.82 | SIRT6 (0.65) | SIRT6KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL13634184 | 0.82 | ALDH1A1 (0.56) | KDM4EALDH1A1LMNARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |