Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 6/20 | 0.44 |
| ▸ | DRD4 | P21917 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634249 | 0.93 | KDM4E (0.58) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL13163940 | 0.87 | KDM4E (0.54) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL13163942 | 0.84 | KDM4E (0.57) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL13163981 | 0.83 | KDM4E (0.52) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL13634181 | 0.82 | SIRT6 (0.49) | ALDH1A1KDM4EMAPTRAB9AMAPK1 | |
| SCHEMBL495753 | 0.81 | KDM4E (0.62) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL13634309 | 0.80 | KDM4E (0.61) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL378360 | 0.80 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL20257082 | 0.80 | KDM4E (0.62) | ALDH1A1KDM4EMAPK1LMNASMN1; SMN2 | |
| SCHEMBL2774659 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KDM4EMAPTHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |