Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270617 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL13162597 | 0.84 | KDM4E (0.54) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL13634249 | 0.82 | KDM4E (0.58) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL13634184 | 0.80 | ALDH1A1 (0.56) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL13162347 | 0.80 | SIRT6 (0.50) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL13163942 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL13638809 | 0.77 | KDM4E (0.52) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL495753 | 0.77 | KDM4E (0.62) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL13163940 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL221403 | 0.77 | ALDH1A1 (0.81) | KDM4EALDH1A1GAAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |