Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.57 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.57 |
| ▸ | CNR2 | P34972 | 6/20 | 0.56 |
| ▸ | CNR1 | P21554 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22720137 | 1.00 | RAB9A (0.59) | RAB9ANPC1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2060435 | 0.92 | CRBN (0.56) | RAB9ANPC1KDM4EALDH1A1CRBN | |
| Water SCHEMBL28110279 | 0.90 | CRBN (0.55) | RAB9ANPC1KDM4EALDH1A1CRBN | |
| SCHEMBL2771765 | 0.86 | CRBN (0.51) | RAB9ANPC1KDM4EALDH1A1CRBN | |
| SCHEMBL2771766 | 0.86 | CRBN (0.51) | RAB9ANPC1KDM4EALDH1A1CRBN | |
| SCHEMBL28510668 | 0.86 | CRBN (0.51) | RAB9ANPC1KDM4EALDH1A1CRBN | |
| SCHEMBL4960760 | 0.86 | NPC1 (0.53) | RAB9ANPC1KDM4EALDH1A1CRBN | |
| SCHEMBL22720116 | 0.85 | ALDH1A1 (0.66) | RAB9ANPC1CNR2CNR1KDM4E | |
| SCHEMBL13161898 | 0.85 | ALDH1A1 (0.61) | RAB9ANPC1CNR2CNR1KDM4E | |
| SCHEMBL29229446 | 0.84 | ALDH1A1 (0.69) | RAB9ANPC1CNR2CNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |