Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1L | O00429 | 8/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634334 | 0.93 | DNM1L (0.42) | DNM1LHRH3CTSBCTSSCTSK | |
| SCHEMBL15888597 | 0.81 | DNM1L (0.45) | DNM1LHRH3OGACHRM3PDE4A | |
| SCHEMBL13634268 | 0.81 | HRH3 (0.45) | DNM1LHRH3CTSBCTSSCTSK | |
| SCHEMBL10279631 | 0.80 | OGA (0.48) | DNM1LCTSBCTSSCTSKOGA | |
| SCHEMBL22334855 | 0.77 | HRH4 (0.46) | DNM1LHRH3CTSBCTSSCTSK | |
| SCHEMBL2771181 | 0.75 | SMN1; SMN2 (0.50) | DNM1LHRH3OGALMNA | |
| SCHEMBL13634265 | 0.75 | HRH3 (0.42) | HRH3CTSBCTSSCTSKOGA | |
| SCHEMBL2770015 | 0.74 | DNM1L (0.46) | DNM1LHRH3OGA | |
| SCHEMBL3555940 | 0.73 | HRH3 (0.44) | DNM1LHRH3OGACHRM3PDE4A | |
| SCHEMBL13634279 | 0.72 | DNM1L (0.42) | DNM1LHRH3CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |