Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1L | O00429 | 4/20 | 0.42 |
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634188 | 0.93 | DNM1L (0.49) | DNM1LOGACTSBCTSSCTSK | |
| SCHEMBL22334855 | 0.83 | HRH4 (0.46) | DNM1LOGACTSBCTSSCTSK | |
| SCHEMBL13634265 | 0.81 | HRH3 (0.42) | OGACTSBCTSSCTSKHRH4 | |
| SCHEMBL3555940 | 0.80 | HRH3 (0.44) | DNM1LOGAHRH3NPC1RAB9A | |
| SCHEMBL13634266 | 0.78 | HRH3 (0.46) | OGACTSBCTSSCTSKHRH3 | |
| SCHEMBL10279631 | 0.77 | OGA (0.48) | DNM1LOGACTSBCTSSCTSK | |
| SCHEMBL13634268 | 0.76 | HRH3 (0.45) | DNM1LOGACTSBCTSSCTSK | |
| SCHEMBL13634269 | 0.75 | OGA (0.41) | OGACTSBCTSSCTSKHRH3 | |
| SCHEMBL18674615 | 0.74 | OGA (0.40) | OGACTSBCTSSCTSKALDH1A1 | |
| SCHEMBL22334924 | 0.74 | MAPT (0.57) | OGANPC1RAB9ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |