Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | OGA | O60502 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.37 |
| ▸ | DNM1L | O00429 | 5/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634265 | 0.92 | HRH3 (0.42) | HRH3CTSBCTSSCTSKOGA | |
| SCHEMBL13634205 | 0.86 | OGA (0.39) | HRH3CTSBCTSSCTSKDGAT2 | |
| SCHEMBL13634266 | 0.83 | HRH3 (0.46) | HRH3MAP4K4CTSBCTSSCTSK | |
| SCHEMBL10278217 | 0.82 | HRH3 (0.48) | HRH3MAP4K4DGAT2OGAPIN1 | |
| SCHEMBL13634188 | 0.81 | DNM1L (0.49) | HRH3CTSBCTSSCTSKDGAT2 | |
| SCHEMBL10279631 | 0.78 | OGA (0.48) | CTSBCTSSCTSKOGADNM1L | |
| SCHEMBL3436064 | 0.77 | HRH3 (0.40) | HRH3MAP4K4DGAT2PIN1DNM1L | |
| SCHEMBL13999803 | 0.77 | ALDH1A1 (0.47) | HRH3OGALMNANPC1ALDH1A1 | |
| SCHEMBL3554282 | 0.77 | HRH3 (0.44) | HRH3MAP4K4OGAPIN1LMNA | |
| SCHEMBL13634334 | 0.76 | DNM1L (0.42) | HRH3CTSBCTSSCTSKOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |