SCHEMBL13634279

SCHEMBL13634279

CCc1csc(N2CCC[C@@H]2C)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1L O00429 1/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 1/20 0.40
F2RL3 Q96RI0 2/20 0.38
F2 P00734 1/20 0.38
LMNA P02545 1/20 0.38
CTSB P07858 1/20 0.37
CTSS P25774 1/20 0.37
CTSK P43235 1/20 0.37
PIM1 P11309 1/20 0.36
PIM3 Q86V86 1/20 0.36
PIM2 Q9P1W9 1/20 0.36
OGA O60502 1/20 0.36
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HRH3 Q9Y5N1 2/20 0.35
SMARCA2 P51531 1/20 0.34
SMARCA4 P51532 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20548132 0.82 DNM1L (0.47) DNM1LMEN1KMT2AALDH1A1HPGD
SCHEMBL21875300 0.82 DNM1L (0.47) DNM1LMEN1KMT2AALDH1A1HPGD
SCHEMBL3556057 0.80 L3MBTL1 (0.46) DNM1LMEN1KMT2AALDH1A1HPGD
SCHEMBL16603221 0.79 F2RL3 (0.44) F2RL3PDE10A
SCHEMBL13634271 0.78 IRAK4 (0.39) OGA
SCHEMBL13634270 0.76 CTSB (0.40) DNM1LALDH1A1HPGDCTSBCTSS
SCHEMBL10136902 0.75 ALDH1A1 (0.49) DNM1LMEN1KMT2AALDH1A1HPGD
SCHEMBL13999772 0.75 ALDH1A1 (0.39) DNM1LMEN1KMT2AALDH1A1HPGD
SCHEMBL10279631 0.74 OGA (0.48) DNM1LCTSBCTSSCTSKOGA
SCHEMBL3550331 0.74 PTGER1 (0.46) DNM1LMEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 US disclosed