Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13163108 | 0.93 | EPHX2 (0.42) | EPHX2TTRCYP2C19KDM4EACACB | |
| SCHEMBL13634331 | 0.90 | EPHX2 (0.34) | EPHX2TTRCYP2C19KDM4EACACB | |
| SCHEMBL13634347 | 0.87 | KDM5A (0.44) | EPHX2TTRACACBLIPGLPL | |
| SCHEMBL13638977 | 0.85 | KDM4E (0.35) | EPHX2TTRCYP2C19KDM4ERBP4 | |
| SCHEMBL13634226 | 0.85 | KDM4E (0.35) | EPHX2TTRCYP2C19KDM4ERBP4 | |
| SCHEMBL13634332 | 0.82 | SCD5 (0.39) | TTRACACB | |
| SCHEMBL13270556 | 0.81 | EPHX2 (0.38) | EPHX2CYP2C19KDM4EACACBCYP2C9 | |
| SCHEMBL13163111 | 0.80 | EPHX2 (0.47) | EPHX2TTRRBP4 | |
| SCHEMBL13162352 | 0.79 | EPHX2 (0.36) | EPHX2CYP2C19CYP2C9CYP2J2 | |
| SCHEMBL13162581 | 0.79 | TTR (0.39) | TTRLIPGLPLLIPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |