Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPC | P11150 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13163111 | 0.94 | EPHX2 (0.47) | KDM5APDE3BPDE3APDE10AEPHX2 | |
| SCHEMBL13634225 | 0.87 | EPHX2 (0.38) | EPHX2ACACBTTRLIPGLPL | |
| SCHEMBL15888603 | 0.86 | HCRTR1 (0.46) | KDM5APDE3BPDE3APDE10AEPHX2 | |
| SCHEMBL13270615 | 0.82 | EPHX2 (0.42) | KDM5APDE3BPDE3APDE10AEPHX2 | |
| SCHEMBL13163108 | 0.80 | EPHX2 (0.42) | EPHX2ACACBTTR | |
| SCHEMBL15888646 | 0.80 | HCRTR1 (0.46) | KDM5APDE3BPDE3APDE10AEPHX2 | |
| SCHEMBL13634302 | 0.80 | PDE3B (0.47) | KDM5APDE3BPDE3APDE10AEPHX2 | |
| SCHEMBL13634228 | 0.79 | EPHX2 (0.45) | EPHX2ACACBRET | |
| SCHEMBL13634332 | 0.78 | SCD5 (0.39) | RIPK1ACACBTTR | |
| SCHEMBL13638965 | 0.77 | PDE3B (0.45) | KDM5APDE3BPDE3APDE10AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |