Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 3/20 | 0.33 |
| ▸ | TTR | P02766 | 3/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638977 | 1.00 | KDM4E (0.35) | KDM4ECYP2C19CTSVCTSLCTSB | |
| SCHEMBL15888555 | 0.86 | HCRTR2 (0.43) | KDM4EIDH1HCRTR2KMT2AHCRTR1 | |
| SCHEMBL13634225 | 0.85 | EPHX2 (0.38) | KDM4ECYP2C19RBP4TTREPHX2 | |
| SCHEMBL13634787 | 0.84 | HCAR2 (0.40) | KDM4EKMT2AIRAK4 | |
| SCHEMBL13270803 | 0.84 | HCAR2 (0.40) | KDM4EKMT2AIRAK4 | |
| SCHEMBL13163108 | 0.83 | EPHX2 (0.42) | KDM4ECYP2C19RBP4TTRKMT2A | |
| SCHEMBL13634770 | 0.82 | PIM1 (0.36) | CYP2C19RBP4IRAK4 | |
| SCHEMBL13634331 | 0.80 | EPHX2 (0.34) | KDM4ECYP2C19TTRKMT2AEPHX2 | |
| SCHEMBL13634860 | 0.79 | POLB (0.43) | KDM4EKMT2A | |
| SCHEMBL13634417 | 0.79 | HRH4 (0.31) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |