Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634225 | 0.90 | EPHX2 (0.38) | EPHX2TTRKDM4ECYP2C19ACACB | |
| SCHEMBL13163108 | 0.88 | EPHX2 (0.42) | EPHX2TTRKDM4ECYP2C19ACACB | |
| SCHEMBL15888602 | 0.83 | HCRTR1 (0.43) | KDM4EACACBL3MBTL1PDE10AMEN1 | |
| SCHEMBL13162352 | 0.81 | EPHX2 (0.36) | EPHX2CYP2C19PDE10A | |
| SCHEMBL13634226 | 0.80 | KDM4E (0.35) | EPHX2TTRKDM4ECYP2C19KMT2A | |
| SCHEMBL13638977 | 0.80 | KDM4E (0.35) | EPHX2TTRKDM4ECYP2C19KMT2A | |
| SCHEMBL13162789 | 0.80 | RIPK1 (0.36) | TTRKDM4EITGALLMNAL3MBTL1 | |
| SCHEMBL13634347 | 0.77 | KDM5A (0.44) | EPHX2TTRACACBPDE10A | |
| SCHEMBL13162582 | 0.76 | IRAK4 (0.36) | KDM4EITGALGSK3BDYRK1A | |
| SCHEMBL13634366 | 0.75 | PDE9A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |