Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 10/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634245 | 0.85 | PDE3B (0.41) | EPHX2RET | |
| SCHEMBL13634246 | 0.82 | OGA (0.36) | EPHX2CYP2C9RET | |
| SCHEMBL15888649 | 0.80 | NAAA (0.43) | NAAAEPHX2CYP2C9RETKDM4E | |
| SCHEMBL13634302 | 0.79 | PDE3B (0.47) | EPHX2RET | |
| SCHEMBL13162320 | 0.79 | NAAA (0.43) | NAAAEPHX2CYP2C9CHRM2CHRM1 | |
| SCHEMBL13634327 | 0.78 | DPP4 (0.41) | RET | |
| SCHEMBL13634228 | 0.78 | EPHX2 (0.45) | NAAAEPHX2CYP2C9CHRM2CHRM1 | |
| SCHEMBL13634416 | 0.77 | KDM4E (0.34) | KDM4E | |
| SCHEMBL13634244 | 0.76 | HRH3 (0.42) | NAAA | |
| SCHEMBL13634325 | 0.75 | ACACB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |