Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | DNM1L | O00429 | 4/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.36 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 2/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16603221 | 0.79 | F2RL3 (0.44) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL13270380 | 0.78 | LDHA (0.47) | ADORA2AADORA1ADORA3ADORA2BCUL4A | |
| SCHEMBL13162773 | 0.77 | MTOR (0.34) | ADORA2AADORA1ADORA3ADORA2BCUL4A | |
| SCHEMBL13634279 | 0.76 | DNM1L (0.42) | CTSBCTSSCTSKDNM1LALDH1A1 | |
| SCHEMBL20548132 | 0.74 | DNM1L (0.47) | DNM1LKDM4EALDH1A1TP53MAPT | |
| SCHEMBL21875300 | 0.74 | DNM1L (0.47) | DNM1LKDM4EALDH1A1TP53MAPT | |
| SCHEMBL13634335 | 0.74 | PDE10A (0.35) | CTSBCTSSCTSK | |
| SCHEMBL16594480 | 0.73 | F2RL3 (0.43) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL15356979 | 0.73 | F2RL3 (0.43) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL10279631 | 0.72 | OGA (0.48) | CTSBCTSSCTSKDNM1LTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |