Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634222 | 0.78 | PTGER1 (0.38) | PDE10A | |
| SCHEMBL15888542 | 0.77 | GAA (0.47) | OGA | |
| SCHEMBL13638848 | 0.77 | PDE10A (0.32) | PDE10A | |
| SCHEMBL13634270 | 0.74 | CTSB (0.40) | CTSBCTSSCTSK | |
| SCHEMBL13634282 | 0.72 | — | — | |
| SCHEMBL13634334 | 0.71 | DNM1L (0.42) | OGACTSBCTSSCTSK | |
| SCHEMBL13634188 | 0.68 | DNM1L (0.49) | OGACTSBCTSSCTSK | |
| SCHEMBL13634283 | 0.66 | ADORA2A (0.35) | DPP4 | |
| SCHEMBL13634279 | 0.65 | DNM1L (0.42) | PDE10AOGACTSBCTSSCTSK | |
| SCHEMBL3541650 | 0.64 | RAB9A (0.45) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |