Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13161888 | 0.83 | SIRT6 (0.47) | KDM4EALDH1A1MAPTGRM2FGFR1 | |
| SCHEMBL2774659 | 0.81 | ALDH1A1 (0.59) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL20286049 | 0.81 | SMN1; SMN2 (0.54) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| Hydrochloric Acid SCHEMBL2769406 | 0.80 | ALDH1A1 (0.58) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL7863409 | 0.77 | GRM2 (0.48) | ALDH1A1MAPTGRM2FGFR1FGFR2 | |
| SCHEMBL13634309 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL13634159 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL13163941 | 0.76 | ALDH1A1 (0.53) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL13163981 | 0.76 | KDM4E (0.52) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL13634249 | 0.75 | KDM4E (0.58) | KDM4EALDH1A1GAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |